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colorectal cancer

HIG1 Domain Family Member 1A Disrupts Proliferation, Migration and Invasion of Colon Adenocarcinoma Cells

[Bioengineered] Higd-1a promotes the proliferation of pancreatic cancer cells and the growth of pancreatic cancer; however, no similar observations have been reported for colorectal cancer (CRC). This study, researchers verified the role of Higd-1a in colorectal cancer.

Combination of Resveratrol and BIBR1532 Inhibits Proliferation of Colon Cancer Cells by Repressing Expression of LncRNAs

[Medical Oncology] Scientists investigated the effect of resveratrol and BIBR1532, either alone or in combination, on the cell viability as well as on expression of long non-coding RNAs for HT-29 colon adenocarcinoma cells.

Elevar Therapeutics Receives Orphan Drug Designation from FDA for Rivoceranib for the Treatment of Hepatocellular Carcinoma (HCC)

[Hepatic Cell News] Elevar Therapeutics, Inc. announced that the US FDA has granted rivoceranib with orphan drug designation for the treatment of HCC, the most common primary liver malignancy and is a leading cause of cancer-related death worldwide.

Cetuximab Promotes RSL3-Induced Ferroptosis by Suppressing the Nrf2/HO-1 Signalling Pathway in KRAS Mutant Colorectal Cancer

[Cell Death & Disease] Researchers investigated whether cetuximab-mediated regulation of p38/Nrf2/HO-1 promoted RSL3-induced ferroptosis and played a pivotal role in overcoming drug resistance in KRAS mutant colorectal cancer.

Tumor Suppressor LHX6 Upregulation Contributes to the Inhibitory Effect of miR-346 Knockdown on Colorectal Cancer Cell Growth

[Environmental Toxicology] Dysregulated miRNAs have been promulgated as oncogenes or tumor-suppressive genes participating in the initiation and progression of colorectal cancer (CRC). Scientists reported that miR-346 was highly expressed in CRC patients.

Proteasome Inhibitors Restore the STAT1 Pathway and Enhance the Expression of MHC Class I on Human Colon Cancer Cells

[Journal of Biomedical Science] Scientists applied three colon cancer cell lines, including microsatellite stable cell lines, which are SW480 and SW620, and microsatellite instability-high cell line, which is DLD-1.

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