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dengue

Lyn Kinase Regulates Egress of Flaviviruses in Autophagosome-Derived Organelles

[Nature Communications] Scientists investigated how flaviviruses exploit Src family kinases for exit from infected cells. They identifyied Lyn as a critical component for secretion of Dengue and Zika infectious particles and their corresponding virus like particles

Sequential Immunization Induces Strong and Broad Immunity against All Four Dengue Virus Serotypes

[NPJ Vaccines] Scientists tested whether sequential immunization induces stronger and broader immunity against four dengue virus serotypes than tetravalent-formulated immunization.

TLR2 on Blood Monocytes Senses Dengue Virus Infection and Its Expression Correlates with Disease Pathogenesis

[Nature Communications] Scientists demonstrated that TLR2, together with its co-receptors CD14 and TLR6, was an innate sensor of Dengue virus particles inducing inflammatory cytokine expression and impairing vascular integrity in vitro.

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