dermal cells

[Lab On A Chip] Investigators grew and differentiated human keratinocytes within a microfluidic chip to construct an integrated epidermis-on-a-chip system, which was specially designed to integrate multi-culture units with integrated bubble removal structure.

[Molecular Medicine Reports] The authors determined whether Lycopus lucidus Turcz (LLT) could improve 2,4‑dinitrochlorobenzene‑induced dermatitis and to verify the inhibitory effect of LLT on the expression of chemokines and pro‑inflammatory cytokines in the HaCaT immortalized keratinocyte cell line.

[Advanced Science] By forced expression of the ectodysplasin-A in human epidermal keratinocytes sweat gland (SwG) culture medium, human epidermal keratinocytes were efficiently converted into SwG cells.

[eLife] The authors used a highly specific integrin α5β1 peptidomimetic combined with nanopatterned hydrogels to show that keratinocyte sheets regulated their migration ability at an optimal integrin α5β1 nanospacing.

[Journal of Cell Biology] Researchers conducted culture experiments that proved epidermal growth factor receptor (EGFR) activation drove human keratinocyte stem cell motility.

[Scientific Reports] Researchers investigated whether mechanical energy transported by low intensity ultrasound could generate a mechanical stress able to induce the release of inflammatory cytokine such as interleukin-6 in the human keratinocyte cell line, HaCaT.