dermal cells

[Scientific Reports] Keratinocytes derived from hypertrophic scar tissue were cultured and expression of proliferation markers, activation markers, differentiation markers, apoptosis factors, and proliferation/differentiation regulators was investigated to compared with that of those in keratinocytes derived from normal skin tissue.

[International Journal of Biological Macromolecules] Researchers presented alginate, gelatin and diethylaminoethyl cellulose based bioink formulation and its application in bioprinting and biofabrication of skin tissue equivalents.

[Toxicology in Vitro] Investigators evaluated the effects of electronic cigarette (EC) refill fluids and EC exhaled aerosol residue on cultured human keratinocytes and MatTek EpiDerm™, a 3D air liquid interface human skin model.

[Scientific Reports] Scientists investigated the chemical components of the F. dubia sap extracted by liquid chromatography-electrospray ionization quadrupole time-of-flight mass spectrometry and its potential use in cosmetics in terms of cellular antioxidation on keratinocytes, phototoxicity, and irritation on 3D skin cell models following standard tests suggested by the Organization for Economic Cooperation and Development.

[International Journal of Pharmaceutics] The obtained nanoparticles have shown low toxicity in keratinocytes, however, higher loadings of cannabidiol or curcumin resulted in increased toxicity. The nanoparticles effectively internalized into keratinocytes, implying their applicability for dermal delivery.

[Nature Protocols] Investigators detailed a six-stage planar differentiation methodology for generating human pluripotent stem cell–derived pancreatic β cells that secreted high amounts of insulin in response to glucose stimulation.