dermal cells

[Molecular Therapy-Oncolytics] The authors summarize the recent research progress on the effects of non-coding RNAs (ncRNAs) on melanoma and attempt to elucidate the role of ncRNAs as molecular markers or potential targets will provide promising application perspectives of melanoma.

[npj Microgravity] Investigators showed that under time-averaged simulated microgravity, the thickness of the endothelial cell arrangement increased by up to 59.75%, indicating skin irritation due to vasodilation, and that the diameter of keratinocytes and fibroblast co-cultured spheroids decreased by 6.66%, representing skin thinning.

[Nature Communications] Scientists used centrosomes, that organize the mitotic spindle, to test whether cell division orientation and stratification are linked.

[Journal of Clinical Investigation] Researchers used both pharmacologic and genetic approaches in cells and mice to show that both the platelet-activating factor receptor and enzyme acid sphingomyelinase were necessary for UVB-MVP generation.

[Scientific Reports] Investigators tested the effects of Methylene blue on UVB ray-induced DNA double-strand breaks in primary human keratinocytes.

[Cell Death Discovery] Investigators demonstrated that melanocortin-1 receptor (MC1R) is a critical factor in chromosome stability and centromere integrity in melanocytes. α-MSH/MC1R stimulation prevents melanocytes from UV radiation-induced damage of chromosome stability and centromere integrity.