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endothelial cells

Endothelial Glycocalyx Is Damaged in Diabetic Cardiomyopathy: Angiopoietin 1 Restores Glycocalyx and Improves Diastolic Function in Mice

[Diabetologia] Scientists hypothesized that endothelial glycocalyx damage in the coronary microcirculation contributed to increased microvascular permeability and hence to cardiac dysfunction.

Scutellarin Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting TNFα-Induced Vascular Endothelial Barrier Breakdown

[Acta Pharmacologica Sinica] Researchers suggested that Scutellarin reduced triple-negative breast cance metastasis by suppressing tumor necrosis factor-α (TNFα)-initiated vascular endothelial barrier breakdown through rescuing the reduced expression of junctional proteins by regulating the TNF receptor 2-extracellular signal-regulated protein kinase1/2-enhancer of zeste homolog-2 signaling pathway.

Trimetazidine Enhances Myocardial Angiogenesis in Pressure Overload-Induced Cardiac Hypertrophy Mice through Directly Activating Akt and Promoting the Binding of HSF1 to VEGF-A Promoter

[Acta Pharmacologica Sinica] The authors investigated the effects of TMZ on myocardial angiogenesis in pressure overload-induced cardiac hypertrophy mice.

Angiogenic Role of Mesothelium-Derived Chemokine CXCL1 During Unfavorable Peritoneal Tissue Remodeling in Patients Receiving Peritoneal Dialysis as Renal Replacement Therapy

[Frontiers in Immunology] The angiogenic potential of mesothelial cell-derived CXC chemokine ligand 1 (CXCL1) was assessed in vitro by measuring endothelial tube formation of human microvascular endothelial cells treated with conditioned medium from human peritoneal mesothelial cells stimulated to release CXCL1 by treatment with either recombinant IL-17 or peritoneal dialysis effluent.

Autophagy and Skin Wound Healing

[Burns & Trauma] Understanding the relationship between autophagy and skin wound healing may provide novel strategies for the clinical treatment of wound healing.

Lecanoric Acid Mediates Anti-proliferative Effects by an M Phase Arrest in Colon Cancer Cells

[Biomedicine & Pharmacotherapy] Scientists performed cytotoxicity, cell colony, cell cycle and apoptosis assays in various cell lines or primary immune cells.

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