endothelial cells

[American Journal of Physiology-Lung Cellular and Molecular Physiology] The authors demonstrated that antibody-induced leukemia inhibitory factor (LIF) blockade remodeled the lung epithelial transcriptome in association with increased apoptosis.

[Oncogene] Researchers reported that phenazine biosynthesis-like domain-containing protein (PBLD) inhibited hypoxia-induced angiogenesis via ERK/HIF-1a/VEGF axis in HCC cells.

[Oncogene] Phenazine biosynthesis-like domain-containing protein (PBLD) exerted an inhibitory effect on angiogenesis not only via blocking the VEGFR2 expression in endothelial cells, but also through downregulating HIF-1a-induced VEGF expression and secretion in hepatocellular carcinoma cells.

[Scientific Reports] Scientists provided a systematic metabolic comparison of endothelial cells derived from chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension patients.

[Arteriosclerosis Thrombosis and Vascular Biology] Scientists discuss key findings from the latest research that give insight into the mechanisms by which clonal expansion of vascular cells contributes to disease pathology.

[Cell Reports] Scientists evaluated the global mapping of VEGF-mediated dynamic transcriptional events, focusing on major histone-code profiles using chromatin immunoprecipitation sequencing.