endothelial cells

[Journal of Cell Science] Scientists developed an endothelial cell (EC) profiling tool (ECPT) to examine individual cells within intact monolayers. They used ECPT to characterize different phenotypes in arterial, venous and microvascular EC populations.

[Journal of Clinical Investigation] The authors developed a therapeutic regimen consisting of the combination of human PSC-derived corneal endothelial precursors with nicotinamide for effective treatment of corneal endothelial dysfunction.

[Adipocyte] The authors provided in vivo evidence that lysosomal acid lipase-deficiency impaired proliferation of endothelial cells in thermogenic adipose tissue.

[Cell Reports] Investigators confirmed that CXCL4 directly induced myofibroblast differentiation and collagen synthesis in different precursor cells, including endothelial cells, by stimulating endothelial-to-mesenchymal transition.

[iScience] Scientists captured the kinetics of multi-omics layers, such as miRNome, targeted transcriptome, proteome, and metabolome, in irradiated primary human endothelial cells cultured in vitro.

[ACS Nano] The authors constructed a cocktail therapy to simultaneously regulate the osteoblast/osteoclast and M1/M2 macrophage balance.