endothelial progenitor cells

[Journal of Cellular and Molecular Medicine] The in vivo results showed that FGF21 efficiently improved blood perfusion and ischaemic angiogenesis in both type 1 and type 2 diabetic mice, and these effects were accompanied by enhanced endothelial progenitor cells mobilization and infiltration into ischemic muscle tissues and increases in plasma stromal cell–derived factor‐1 concentration.

[Stem Cell Research & Therapy] Transplanted endothelial progenitor cells labelled with PKH26 were attached to the injured luminal surface the first day after balloon injury.

[Current Stem Cell Research & Therapy] Human peripheral blood-derived endothelial progenitor cells were cultured under microgravity (MG) or normal gravity (NG) followed by analysis for angiogenic gene expression. Furthermore, the serum-free cultured medium under MG or NG were collected, and their pro-angiogenic properties were examined in HUVECs.

[Scientific Reports] Hyaluronan synthase 2 was strongly expressed in endothelial progenitor cells in the thickened intima. Moyamoya disease lesions showed minimal staining for chondroitin sulfate and hyaluronan in the endothelium, in contrast to control endothelium showing positive staining for both.

[Scientific Reports] Investigators tested whether fenofibrate, with its anti-inflammatory and vasoprotective effects, could improve myocardial function by activating endothelial progenitor cells through the eNOS pathway in a doxorubicin-induced cardiomyopathy mouse model.

[Cardiovascular Drugs and Therapy] Scientists explored the effect of proprotein convertase subtilisin kexin type 9 inhibitors on circulating endothelial progenitor cells hypothesizing a possible pleiotropic effect.