enterocytes

[Nature Communications] Scientists investigated early infection events using both Trichuris muris infections of mice and murine caecaloids, the first in vitro system for whipworm infection and organoid model for live helminths.

[Scientific Reports] Investigators used selective small molecule inhibitors of monoacylglycerol acyltransferase 2 (MGAT2) and MGAT3 to determine the contributions of these enzymes to triacylglycerol production in liver cells.

[Scientific Reports] The authors showed that l-glutamine stimulation at embryonic day 17 significantly increased enterocyte and microvilli dimensions by 10 and 20%, respectively, within 48 hours.

[Journal of Controlled Release] Researchers developed an advanced three-dimensional in vitro intestinal model to test absorption in a more reliable manner, by better mimicking the native environment.

[Cell Death & Disease] Researchers showed that ERp29 was a novel target for microRNA-135a-5p to inhibit the progression of colorectal cancer (CRC); correspondingly, ERp29 acted as an oncoprotein in CRC by promoting proliferation and metastasis of CRC cells, and suppressing apoptosis of the cells.

[Gut] Cholestatic and non-alcoholic fatty liver disease share several key pathophysiological mechanisms which can be targeted by novel therapeutic concepts that are currently developed for both areas.