enterocytes

[Developmental Cell] Scientists showed that in Drosophila intestine autophagy lowered the sensitivity of differentiated enterocytes to reactive oxygen species that were produced in response to commensal bacteria.

[Journal of Crohns & Colitis] Clinical parameters of colitis were assessed by colonoscopy, histology, flow cytometry and detection of serum biomarkers; single-cell RNA sequencing and qRT-PCR were used to evaluate the effects of cannabinoids on enterocytes.

[Cell Death & Disease] Researchers found that mitochondrial DNA (mtDNA)-mediated STING signaling triggered necroptosis through synergistic IFN and TNF-α signaling in primary IECs.

[Archives of Toxicology] Scientists aimed to assess the expression of the most common intestinal CYP enzymes in a human induced pluripotent stem cell-derived human intestinal organoid model, and the suitability of that model to study chemical-induced changes in CYP expression and activity.

[Molecular Biology of the Cell] Scientists implicate Musashi1 in mouse postnatal development of multiple organs, with Notch signaling alterations contributing to intestinal defects.

[FASEB Journal] OSTERIX, an OB‐specific zinc finger‐containing transcription factor was for the first time found to be expressed in gastrointestinal crypt cells, and SHP2 expression in the crypt Osx+ cells was critical for self‐renewal and proliferation.