extracellular matrix

[Scientific Reports] Researchers investigated the integrin-mediated adhesion between cancer cells and their Arg-Gly-Asp motif displaying biomimetic substratum using the HeLa cell line transfected by the Fucci fluorescent cell cycle reporter construct.

[Fuse Medical, Inc.] Fuse Medical, Inc. announced the official launch of the FuseChoice™ Dermal Matrix line. FuseChoice™ Derm has been developed by using a proprietary process to preserve the inherent properties of key extracellular matrix molecules, such as collagen and elastin, while maintaining excellent tensile strength to maintain its framework with intact vascular channels.

[Laboratory Investigation] Scientists investigated the roles of Lipocalin 2 (LCN2) in chronic inflammation and fibrosis, using repeated carbon tetrachloride in mineral-oil injection. Hepatic and serum LCN2 levels were remarkably higher in the mineral oil-injected wild type group compared to the CCl4.

[Scientific Reports] Performing in situ hybridization and immunofluorescence analysis, researchers found that mouse Hmcn1 and Hmcn2 showed a complementary distribution throughout different tissues and developmental stages.

[NPJ Regenerative Medicine] Investigators proposed a methodology to fabricate hierarchical multiscale scaffolds with controlled hydrophilic and hydrophobic properties by employing capillary force lithography in combination with plasma modification.

[Scientific Reports] Scientists reported the development of a novel, flowable, thermosensitive, injectable drug delivery system comprising bovine collagen (BC) and fibrinogen (FB) that formed a solid BC/FB gel immediately upon exposure to physiological conditions and could be used to deliver reparative drugs, such as the naturally occurring anti-inflammatory, anti-scarring agent Decorin, into adult rat spinal cord lesion sites.