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hepatic cells

Long Noncoding RNA SNHG1 Silencing Accelerates Hepatocyte-Like Cell Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells to Alleviate Cirrhosis via the microRNA-15a/SMURF1/UVRAG Axis

[Cell Death Discovery] Researchers investigated whether long noncoding RNA SNHG1 was involved in cirrhosis by affecting hepatocyte-like cell differentiation of bone marrow-derived MSCs.

Bioinspired NiO Nanospheres: Exploring In Vitro Toxicity Using Bm-17 and L. rohita Liver Cells, DNA Degradation, Docking, and Proposed Vacuolization Mechanism

[ACS Omega] Researchers demonstrated a novel Cleome simplicifolia-mediated green fabrication of nickel oxide (NiO) nanoparticles to explore in vitro toxicity in Bm-17 and Labeo rohita liver cells.

Resveratrol Induces the Fasting State and Alters Circadian Metabolism in Hepatocytes

[Plant Foods For Human Nutrition] Investigators studied the metabolic effect of resveratrol around the circadian clock in order to determine more accurately the hepatic signaling pathways involved. AML-12 hepatocytes were treated with resveratrol and clock and metabolic markers were measured around the clock.

Cell Adhesion Molecule KIRREL1 Is a Feedback Regulator of Hippo Signaling Recruiting SAV1 to Cell-Cell Contact Sites

[Nature Communications] The authors suggested that KIRREL1 functioned as a feedback regulator of the mammalian Hippo pathway through sensing cell-cell interaction and recruiting SAV1 to cell-cell contact sites.

Mimicking Native Liver Lobule Microarchitecture In Vitro with Parenchymal and Non-Parenchymal Cells Using 3D Bioprinting for Drug Toxicity and Drug Screening Applications

[ACS Applied Materials & interfaces] A physiologically relevant human vascularized liver model was bioprinted with a novel liver extracellular matrix-based bioink laden with human adipose mesenchymal stem cell-derived hepatocyte-like cells, human umbilical vein endothelial cells, and human hepatic stellate cells.

Growth Hormone and Insulin-Like Growth Factor I Regulation of Nonalcoholic Fatty Liver Disease

[Journal of Clinical Endocrinology & Metabolism] Investigators focus on the potential role of growth hormone and insulin-like growth factor I in the regulation of hepatic steatosis, inflammation, and fibrosis.

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