in vivo

[Cell Death & Disease] Spry1 knockdown in three BRAFV600-mutant cutaneous melanoma cell lines markedly induced cell cycle arrest and apoptosis, repressed cell proliferation in vitro, and impaired tumor growth in vivo.

[Cell Stem Cell] Researchers showed integrin-linked kinase, a key constituent of focal adhesions, is highly expressed in TKI-nonresponsive patient cells and their LSCs.