induced pluripotent stem cells

[Oncology Reports] Investigators aimed to examine the stemness‑inhibitory effects of dinaciclib in MCF‑7 and HCC‑1806 breast cancer cells.

[Cell Reports] The authors studied the importance of CCL18, a cytokine expressed in human but not in rodent glioma-associated microglia/macrophages, as a modulator of glioma growth.

[Nature Cell Biology] Investigators observed that initiation of differentiation in iPSCs and ESCs triggered widespread apoptosis, followed by a synchronous epithelial–mesenchymal transition.

[Nature] The authors demonstrated, by creating an intermediate plastic state, the chemical reprogramming of human somatic cells to human chemically iPSCs that exhibited key features of ESCs.

[Stem Cell Research] Scientists generated an iPSC line from the peripheral blood mononuclear cells of an otosclerosis patient. The cell line exhibited normal morphology, karyotype, and pluripotency marker expression.

[Stem Cell Reviews and Reports] The authors focus on how to progress in vitro generation of platelets from stem cell, especially iPSCs, and describe some of the successful strategies that can be easily used in clinic.