induced pluripotent stem cells

[Cell & Bioscience] The authors established a robust method allowing rapid derivation of mesenchymal stem cells from both human iPSCs and ESCs via a temporal induction of neural ectoderm in chemically defined media.

[Hepatology Communications] Researchers generated iPSC-derived hepatocytes and iPSC-derived cholangiocytes cells and characterized them based on hepatocyte-specific and cholangiocyte-specific markers.

[Cell Proliferation] Investigators generated ten O-negative hiPSC clones and evaluated their potential for mesoderm formation and erythroid differentiation, then used a perfusion bioreactor system to perform studies with high-density cultures of erythroblasts in vitro.

[EMBO Reports] Scientists used cerebral organoids derived from patients and genome edited-iPSCs to address pathophysiological changes associated with a complex malformation of human cortical development caused by mutations in the echinoderm microtubule-associated protein-like 1 (EML1) gene.

[Birth Defects Research] Scientists describe how differentiation of hiPSCs to specialized cardiac cellular identities facilitates our understanding of the development and pathogenesis of congenital heart disease subtypes.

[Promega Corporation] Promega Corporation, a leader in providing innovative solutions and technical support to the life sciences industry, and FUJIFILM Cellular Dynamics, Inc., a leading global developer and manufacturer of human iPSC technologies, announced a strategic collaboration to advance novel assay development for drug discovery.