insulin

[Nature Communications] Scientists showed that the death receptor TMEM219 was expressed on pancreatic beta cells and that signaling through its ligand insulin-like growth factor binding protein 3 (IGFBP3) led to beta cell loss and dysfunction.

[Cell Metabolism] By screening the expression and functional characterization of olfactory receptors in pancreatic islets, investigators identified Olfr109 as the receptor that detects insulin peptides.

[Cellular Signalling] Scientists investigated whether the lncRNA MEG3 could regulate autophagy and pyroptosis through FOXO1 in pancreatic β-cells.

[Journal of Cellular Physiology] The authors found a highly significant correlation between pregnancy-associated plasma protein (PAPP)-A expression in IPF lung tissue and disease severity as measured by various pulmonary and physical function tests.

[Cytotherapy] Scientists revealed that co-transplantation of umbilical cord mesenchymal stromal cella and autologous bone marrow mononuclear cells in patients with established type 1 diabetes was associated with reduced incidence of chronic diabetes complications.

[Scientific Reports] Investigators expanded and differentiated human basal cells isolated from the nasal and conducting airway to a mature mucociliary epithelial cell layer at air–liquid interface using a medium formulation containing normal resting glucose levels.