insulin

[Nature Cancer] The authors discovered a conserved cancer-testis (CT)-long non-coding RNAs (lncRNA), named lnc-CTHCC, which was highly expressed in the testes and hepatocellular carcinoma.

[Febs Letters] Scientists discuss recent advances in inter-organ communication from the metabolic, immune, and neural system to pancreatic islets, their biological implication in normal pancreas endocrine function, as well as their role in the adaptive responses of islet to nutrition-induced stress.

[Nature Communications] Researchers showed that increased expression of the transcription factor Grainyhead 1 promoted lifespan and pathogen resistance in Caenorhabditis elegans.

[Journal of Cell Science] Researchers showed that insulin secretion sites also contain non-neuronal proteins LL5β and KANK1, which in migrating cells organize exocytotic machinery in the vicinity of integrin-based adhesions.

[Physiological Reports] Scientists monitored changes of the intracellular Ca2+ concentration as an immediate read-out for insulin secretion in live cell experiments.

[Nature Communications] To elucidate the underlying cellular and molecular mechanisms, researchers chronically treated wild-type mice and several newly developed mutant mouse strains with clenbuterol, a selective β2-adrenergic receptor agonist.