insulin

[Bioengineered] The underlying molecular mechanisms of PSP in improving insulin resistance (IR) in skeletal muscle remain unclear. PA induced an IR model in L6 myotubes. After treatment, cell proliferation was measured using the CCK8.

[Trends in Pharmacological Sciences] Beta cell replacement has emerged as an attractive therapeutic alternative to traditional exogenous insulin administration for management of type 1 diabetes.

[Laboratory Investigation] Investigators provided evidence that elevated levels of human SMO showed a strong correlation with elevated levels of insulin-like growth factor 1 receptor and reduced survival in diffuse large B-cell lymphoma.

[Autoimmunity] Scientists reported the use of MSCs for the production and delivery of Gastrin, a peptide hormone that is produced by intestinal cells and fetal islets and can increase β-cell mass, to promote protection from type 1 diabetes.

[Nature] Researchers showed that hormonal FABP4 forms a functional hormone complex with adenosine kinase and nucleoside diphosphate kinase to regulate extracellular ATP and ADP levels.

[Acta Histochemica] Researchers investigated the effect of L-Met on streptozotocin-induced β-cell damage model of diabetes mellitus in Sprague Dawley rats. At the end of study biochemical parameters, immunoblotting, qRT-PCR and ChIP-qPCR were performed.