insulin

[Nature Medicine] Porcine and human stem cell-beta islets made insulin in xenotransplant models, and mouse islets tested in a marginal mass syngeneic transplant model cured diabetes in 92% of recipients within 24–48 hours after transplant.

[Scientific Reports] Researchers investigated the inhibitory effects and underlying governing mechanism of clitorin in a western diet-induced hepatic steatosis mouse model, and in oleic acid-stimulated HepG2 cells.

[Current Opinion in Pharmacology] Glucagon is often administered to counteract severe hypoglycaemia, and commonly used diabetes medications such as GLP-1 analogues, sulfonylureas and SGLT2-inhibitors also affect alpha cells.

[JDRF, Inc. (BioSpace, Inc.)] JDRF, the leading global type 1 diabetes research and advocacy organization, announces a new collaboration with leading diabetes, advocacy, and healthcare partners to support a newly established insulin-centered project from Civica Inc.

[Stem Cell Reports] Scientists described the generation of an array of monoclonal antibodies against cell surface markers that selectively label stem cell-derived islet cells.

[Elgan Pharma (BioSpace, Inc.)] Elgan Pharma released the findings of its Phase III study on the safety and efficacy of an insulin formulation for the treatment of intestinal malabsorption in preterm infants, called ELGN-GI.