islets

[ACS Nano] Investigators described a strategy that utilizes pretargeting and glycochemistry to bioengineer β cells in situ to induce β-cell-specific tolerance.

[FEBS Journal] Investigators found that the RIIB subunit of protein kinase A is expressed specifically by β cells of mouse and human islets.

[PLoS One] Investigators showed that Akr1c19 expression was dramatically decreased in db/db islets.

[Biomedicine & Pharmacotherapy] The authors isolated pancreatic islets from adult male Wistar rats and identified pancreatic β-cells by the cell size, capacitance and membrane potential.

[Science Advances] Scientists developed, characterized, and tested an implantable graphene bioscaffold which elutes dexamethasone that could accommodate islets and adipose tissue–derived MSCs.

[Diabetes] To obtain insight into the role of lipid droplets (LD) in human islet β-cell function, the levels of a key LD scaffold protein, perilipin 2, were manipulated by lentiviral-mediated knockdown or overexpression in EndoCβH2-Cre cells, a human cell line with adult islet β-like properties.