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lineage conversion
Immune Regulation News
Notch2-Mediated Plasticity between Marginal Zone and Follicular B Cells
[Nature Communications] Investigators showed induced Notch2IC-expression in follicular B (FoB) cells re-programs mature FoB cells into bona fide marginal zone B cells as was evident from the surface phenotype, localization, immunological function and transcriptome of these cells.