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lung cancer

Ibrutinib Reverses IL-6-Induced Osimertinib Resistance through Inhibition of Laminin α5/FAK Signaling

[Communications Biology] The authors showed that clinically, plasma interleukin-6 (IL-6) level predicted osimertinib efficacy in epidermal growth factor receptor mutant NSCLC patients.

Quercitrin Restrains the Growth and Invasion of Lung Adenocarcinoma Cells by Regulating Gap Junction Protein Beta 2

[Bioengineered] Quercitrin prohibited the cell viability and clone-formation of lung adenocarcinoma cells in vitro.

Circular RNA-UBE2D2 Accelerates the Proliferation and Metastasis of Non-small Cell Lung Cancer Cells via Modulating microRNA-376a-3p/Eukaryotic Translation Initiation Factor 4γ2 Axis

[Bioengineered] Scientists suggested that circ-UBE2D2 promoted the proliferation, migration and invasion but restrained apoptosis of lung cancer cells by regulating miR-376a-3p/eukaryotic translation initiation factor 4γ2 axis.

Emerging Function and Clinical Significance of Extracellular Vesicle Noncoding RNAs in Lung Cancer

[Molecular Therapy Oncolytics] The authors summarize the biological characteristics and functions of extracellular vesicles ncRNAs in the biological processes of lung cancer (LC), focusing on their potential to serve as diagnostic and prognostic biomarkers of LC as well as their probable role in the clinical treatment of LC.

Targeting the Epigenetic Processes to Enhance Antitumor Immunity in Small Cell Lung Cancer

[Seminars in Cancer Biology] Scientists review current clinical trials of epigenetic therapy against small cell lung cancer and the mechanisms of epigenetic inhibitors to boost antitumor immunity.

Mesenchymal Stem Cell-Based Treatments for COVID-19: Status and Future Perspectives for Clinical Applications

[Cellular and Molecular Life Sciences] Investigators describe the origins, pathogenesis, and clinical features of COVID-19 and the potential uses of MSCs in therapeutic treatments for severe acute respiratory syndrome coronavirus 2-infected patients.

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