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lymphocytes

Characterization of Immune Responses in Fully Vaccinated Individuals Following Breakthrough Infection with the SARS-CoV-2 Delta Variant

[Science Translational Medicine] Vaccinated individuals who tested positive showed higher mucosal antibody responses in nasal secretions and higher Spike protein-specific CD8+ T cell responses in peripheral blood than did vaccinated individuals who tested negative.

Monocytic MDSCs Homing to Thymus Contribute to Age-Related CD8+ T Cell Tolerance of HBV

[Journal of Experimental Medicine] Investigators found that the frequency of hepatitis B surface antigen (HBsAg)-specific CD8+ T cells was inversely correlated with expansion of monocytic myeloid-derived suppressor cells in young rather than in adult chronic hepatitis B patients.

HLA-A*11:01-Restricted CD8+ T Cell Immunity against Influenza A and Influenza B Viruses in Indigenous and Non-Indigenous People

[PLoS Pathogens] Investigators embarked on an epitope discovery study to define a CD8+ T cell landscape for HLA-A*11:01-expressing Indigenous and non-Indigenous Australian people.

Structural and Immunoendocrine Remodeling in Gut, Pancreas and Thymus in Weaning Rats Fed Powdered Milk Diets Rich in Maillard Reactants

[Scientific Reports] Researchers described that weaning rats fed diets rich in Maillard reaction products were affected in both their immune and endocrine systems.

TRAF6-Overexpressing Dendritic Cells Loaded with MUC1 Peptide Enhance Anti-Tumor Activity in B16-MUC1 Melanoma-Bearing Mice

[International Immunopharmacology] Tumor necrosis factor receptor-associated factor 6 (TRAF6)-overexpressing dendritic cells had increased expression of costimulatory molecules, major histocompatibility complex molecules and IL-12 expression.

Mitochondrial-Apoptotic Signaling Involvement in Remodeling during Myogenesis and Skeletal Muscle Atrophy

[Seminars in Cell & Developmental Biology] Scientists review the role of mitochondrial apoptotic signaling in skeletal muscle remodeling during myogenic differentiation and skeletal muscle pathological states, including aging, disuse, and muscular dystrophy.

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