Tag results:
lymphoid cells
Extracellular Matrix News
Targeting of the Tumor Immune Microenvironment by Metformin
[Journal of Cell Communication and Signaling] The authors explain the basic mechanisms for the interactions and communications between immunosuppressive, anti-tumoral, and cancer cells within the tumor microenvironment (TME), and discuss the modulating effects of metformin on various cells and secretions in the TME.
Mesenchymal Cell News
Endometrial Mesenchymal Stem/Stromal Cells: The Enigma to Code Messages for Generation of Functionally Active Regulatory T Cells
[Stem Cell Research & Therapy] The effect of MSCs on proliferation of anti-CD3/CD28-stimulated T CD4+ cells and generation of Tregs with or without pre-treatment with mitomycin C, IFN-γ and IL-1β was evaluated by flow cytometry.
Mesenchymal Cell News
Recellularization of Xenograft Heart Valves Reduces the Xenoreactive Immune Response in an In Vivo Rat Model
[European Journal of Cardio-Thoracic Surgery] Explanted aortic valve constructs from female Hartley guinea pigs were procured and decellularized, followed by recellularization with autologous Sprague-Dawley rat mesenchymal stem cells.
Human Immunology News
Single-Cell Profiling Reveals the Importance of CXCL13/CXCR5 Axis Biology in Lymphocyte-Rich Classic Hodgkin Lymphoma
[Proceedings of the National Academy of Sciences of the United States of America] Researchers examined the immune cell profile of eight cell suspension samples of Lymphocyte-rich classic Hodgkin lymphoma (LR-CHL) in comparison to 20 samples of the mixed cellularity and nodular sclerosis subtypes of CHL.
Human Immunology News
Activation of Toll-Like Receptor 2 Enhances Peripheral and Tumor-Infiltrating CD8+ T Cell Cytotoxicity in Patients with Gastric Cancer
[BMC Immunology] Scientists investigated the regulation of TLR activation to CD8+ T cells has not been fully elucidated in gastric cancer.
Pancreatic Cell News
Designing Biomaterials for the Modulation of Allogeneic and Autoimmune Responses to Cellular Implants in Type 1 Diabetes
[Acta Biomaterialia] Designing materials to decrease antigen escape, improve cell viability, and increase material compatibility are all approaches that can decrease the local release of antigen and danger signals into the implant microenvironment.