lymphoid cells

[Scientific Reports] Researchers elucidated the overall smoking-induced miRNA changes and those specific to chronic obstructive pulmonary disease (COPD).They investigated the downstream effects on regulatory gene expression and the correlation to cellular composition.

[Science Advances] The authors engineered simple-to-implement injectable hydrogels for the controlled co-delivery of CAR-T cells and stimulatory cytokines that improve treatment of solid tumors.

[Cytotherapy] Since Natural Killer (NK)-92 cells do not spontaneously express CCR7, clinical-grade activated NK cells were transfected with a non-viral vector containing the CCR7 receptor, an anti-CD19 CAR and a high-affinity CD16 Fc receptor.

[Journal of Hematology & Oncology] The authors review the mitochondrial characteristics of exhausted T cells and particularly discuss different aspects of mitochondrial metabolism and plasticity.

[Artiva Biotherapeutics, Inc.] rtiva Biotherapeutics, Inc., an oncology company whose mission is to deliver highly effective, off-the-shelf, allogeneic natural killer cell therapies to treat cancer, announced that it has entered into an agreement with Merck, known as MSD outside the United States and Canada.

[Cancer Cell International] The authors indicated a relationship between synaptosome associated protein 25 (SNAP25) expression and prostate cancer, demonstrating that SNAP25 was a potential prognostic biomarker due to its vital role in immune infiltration.