mammary cells

[Journal of Materials Chemistry B] The authors observed that prostate cancer cells and breast cancer cells cultured with nanodiamonds showed morphological changes and altered gene and protein expression.

[Cell Death Discovery] Researchers revealed that F-box and leucine-rich repeat protein 10 (FBXL10) served as a pro-metastatic factor in breast cancer via repressing the expression of E-cadherin and inducing epithelial-mesenchymal transition (EMT).

[Proceedings of the National Academy of Sciences of the United States of America] Scientists studied the dynamical expression of endogenously labeled Hes1, a transcriptional repressor implicated in controlling cell proliferation, to understand how cell-cycle length heterogeneity was generated in estrogen receptor (ER)+ breast cancer cells.

[Scientific Reports] Scientists performed LC/MS metabolic profiling on separated attached and detached MDA-MB-231 cells treated with metformin and/or 2-deoxy-D-glucose and found that the metabolic profile of detached cells was closer to untreated control cells, suggesting detachment might help cells adapt to energy stress.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers demonstrated that calreticulin facilitated breast cancer progression by promoting the breast cancer stem cell phenotype through Wnt/β-catenin signaling in a hypoxia-inducible factor 1 (HIF-1)–dependent manner.

[Molecular Cancer Research] Scientists address the mechanistic progress on how PRK-like endoplasmic reticulum kinase (PERK) acts as a multifunctional molecule to commit 17β-estradiol to inducing apoptosis in endocrine-resistant breast cancer.