mass spectrometry

[Cancer Communications] RNA sequencing of cisplatin-resistant and -sensitive ovarian cancer organoids was performed, followed by detection of the expression level of fibrillin-1 in organoids and clinical specimens of ovarian cancer.

[Cell Death & Disease] The authors reported that hypoxia-inducible factor 1α (HIF-1α) was upregulated after ATP treatment and mediated the ATP-driven chemoresistance process.

[Gastroenterology] Autochthonous murine models of pancreatic cancer (PC) and co-implanted allografts of murine PC cell lines with adipose-derived MSCs were used to assess the role of Muc5ac in stromal heterogeneity.

[International Journal of Oncology] Liquid chromatography‑tandem mass spectrometry and gas chromatography‑mass spectrometry assays were performed, and the results revealed markedly reduced levels of glutamine and metabolic flux in the blood samples of patients with prostate cancer (PCa) and in PCa cells.

[Scientific Reports] Investigators assessed the anti-cancer effects of hibernating common carp plasma on 4T1 cancer cells in vitro and in vivo.

[Cytotherapy] The authors characterized MSCs derived from bone marrow, adipose tissue and umbilical cord tissue for sphingolipids, a class of bioactive lipids, using liquid chromatography/tandem mass spectrometry.