melanocytes

[Pigment Cell & Melanoma Research] The authors summarize the latest insights into various forms of melanocytes death in vitiligo and discuss the corresponding mechanisms.

[Experimental Dermatology] Investigators discuss the pathways governing epithelial and follicular pigmentation, numerous areas of future research and potential points of intervention are highlighted.

[Nutrients] Researchers examined the effect of Lotus seedpod extract (LSE) on melanogenesis and the involved signaling pathways in vitro and in vivo. They showed that non-cytotoxic doses of LSE and its main component epigallocatechin reduced both tyrosinase activity and melanin production in the α-melanocyte stimulating hormone-induced melanoma cells.

[Cancers] Scientists analyze four major signaling pathways implicated in melanomagenesis, TGF-β, MAPK, Wnt/β-catenin and Hyppo signaling, from the complementary point of view of tumor cells and the microenvironment.

[Pigment Cell & Melanoma Research] Investigators review the potential roles of the unfolded protein response/integrated stress response in the etiology of melanoma and vitiligo.

[Genes & Development] The authors used single-cell RNA sequencing with comparative gene expression analysis to elucidate the transcriptional dynamics of melanocyte stem cells through quiescence, activation, and melanocyte maturation.