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mesenchymal stem cells

Melatonin Treatment Improves Human Umbilical Cord Mesenchymal Stem Cell Therapy in a Mouse Model of Type II Diabetes Mellitus via the PI3K/AKT Signaling Pathway

[Stem Cell Research & Therapy] Scientists investigated whether the combination of melatonin and human umbilical cord mesenchymal stem cells (hUC-MSCs) was superior to hUC-MSCs alone in ameliorating high-fat diet and streptozocin-induced type II diabetes mellitus in a mouse model.

Large-Scale Analysis of MicroRNA Expression in Motor Neuron-Like Cells Derived from Human Umbilical Cord Blood Mesenchymal Stem Cells

[Scientific Reports] Human CB-MSCs were isolated and characterized using flow cytometry. Cell differentiation has been induced by combining retinoic acid and sonic hedgehog in a two-step protocol for 14 days.

Essent Biologics Launches Human Mesenchymal Stem Cells for Regenerative Medicine, Biopharmaceutical and Cell Therapy Research

[Essent Biologics™ (PR NewsWire, Inc.)] Essent Biologics™ announced the launch of its human mesenchymal stem cells for regenerative medicine, biopharmaceutical and cell therapy research.

Biomimic Trained Immunity-MSCs Delivery Microcarriers for Acute Liver Failure Regeneration

[Small] A lipopolysaccharide-loaded photoresponsive cryogel porous microcarrier for MSCs delivery and colonization was presented to promote defect liver regeneration.

Menstrual Blood-Derived Mesenchymal Stromal Cells Efficiently Ameliorate Experimental Autoimmune Encephalomyelitis by Inhibiting T Cell Activation in Mice

[Stem Cell Research & Therapy] Researchers evaluated the therapeutic potential of MSCs isolated from menstrual blood as ready-to-use allo-MSCs in multiple sclerosis by application in its animal model experimental autoimmune encephalomyelitis.

Notch1 Activation of Jagged1 Contributes to Differentiation of Mesenchymal Stem Cells into Endothelial Cells under Cigarette Smoke Extract Exposure

[BMC Pulmonary Medicine] In vitro, Jagged1 was found to be activated by Notch1 in MSCs, resulting in the RBP-Jκ-dependent expression of Jagged1 mRNA, a response that was blocked by Notch1 inhibition.

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