Notch1 Activation of Jagged1 Contributes to Differentiation of Mesenchymal Stem Cells into Endothelial Cells under Cigarette Smoke Extract Exposure

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In vitro, Jagged1 was found to be activated by Notch1 in MSCs, resulting in the RBP-Jκ-dependent expression of Jagged1 mRNA, a response that was blocked by Notch1 inhibition.
[BMC Pulmonary Medicine]

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