mesenchymal stem cells

[Biomaterials Science] Researchers constructed a bionic biphasic composite scaffold with on-demand osteochondrogenic factors. Kartogenin and extractive MSCs were introduced into a mPEG-block-poly(L-valine) thermogel set as the upper layer to accelerate cartilage repair.

[Colloids and Surfaces B-Biointerfaces] Rat bone marrow derived MSCs and human umbilical vein endothelial cells were co-cultured onto scaffolds fabricated by the authors to enhance vascularization for bone tissue regeneration.

[Genomics] The authors explored the mechanism of human umbilical cord MSCs-derived extracellular vesicles loaded with miR-223 on myocardial infarction.

[Cytotherapy] Scientists discuss various strategies to consistently maintain or enhance the immunomodulatory potency of MSCs during ex vivo expansion, which will enable the manufacture of allogeneic MSC banks that have high potency and low variability.

[Burns & Trauma] Understanding the relationship between autophagy and skin wound healing may provide novel strategies for the clinical treatment of wound healing.

[Gastroenterology] Autochthonous murine models of pancreatic cancer (PC) and co-implanted allografts of murine PC cell lines with adipose-derived MSCs were used to assess the role of Muc5ac in stromal heterogeneity.