mesenchymal stem cells

[Microscopy Research and Technique] Investigators used an organotypic model of wound healing and we seeded keratinocytes on a adipose-derived MSC-induced dermal matrix. Conventional hematoxylin–eosin stain and immunohistochemistry staining for Ki67, p63 and pan-keratins were performed at different timepoints.

[Journal of Tissue Engineering and Regenerative Medicine] The authors present the current landscape of the field and highlights some interesting findings on MSC-derived extracellular vesicles in the context of COVID-19, including in silico, in vitro, in vivo and case reports.

[Bioengineered] Scientists studied the therapeutic effects of umbilical cord blood-derived mesenchymal stem cells transplantation on adriamycin-induced cardiomyopathy.

[Diabetes Research and Clinical Practice] Scientists attempted to unveil the role of delivery of miR-30c-5p by human umbilical cord mesenchymal stem cells-derived EVs in diabetic retinopathy.

[Stem Cell Research & Therapy] The authors review the recent research advances of therapies based on the mesenchymal stem cells-Exo for treating ulcerative colitis and colorectal cancer.

[Biomaterials] Exosomes from the conditioned medium (CM) of gingival MSC were isolated by ultracentrifugation and were injected into the vitreous of mice. The results showed that intraocular injection of TNF-α-stimulated gingival MSC into mice with ischemia-reperfusion injury notably reduced inflammation and cell loss than that with G-exos.