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mesenchymal stem cells

Mesenchymal Stem Cell-Derived Extracellular Vesicles in the Management of COVID19-Associated Lung Injury: A Review on Publications, Clinical Trials and Patent Landscape

[Journal of Tissue Engineering and Regenerative Medicine] The authors present the current landscape of the field and highlights some interesting findings on MSC-derived extracellular vesicles in the context of COVID-19, including in silico, in vitro, in vivo and case reports.

HucMSC-Derived Exosomes Delivered BECN1 Induces Ferroptosis of Hepatic Stellate Cells via Regulating the xCT/GPX4 Axis

[Cell Death & Disease] Researchers studied the proferroptosis effect and mechanism of mesenchymal stem cell-ex in hepatic stellate cells.

Transplantation of Umbilical Cord Blood-Derived Mesenchymal Stem Cells as Therapy for Adriamycin Induced-Cardiomyopathy

[Bioengineered] Scientists studied the therapeutic effects of umbilical cord blood-derived mesenchymal stem cells transplantation on adriamycin-induced cardiomyopathy.

Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Relieves Diabetic Retinopathy through a microRNA-30c-5p-Dependent Mechanism

[Diabetes Research and Clinical Practice] Scientists attempted to unveil the role of delivery of miR-30c-5p by human umbilical cord mesenchymal stem cells-derived EVs in diabetic retinopathy.

The Therapeutic Potential of Stem Cell-Derived Exosomes in the Ulcerative Colitis and Colorectal Cancer

[Stem Cell Research & Therapy] The authors review the recent research advances of therapies based on the mesenchymal stem cells-Exo for treating ulcerative colitis and colorectal cancer.

TNF-α Stimulation Enhances the Neuroprotective Effects of Gingival MSCs Derived Exosomes in Retinal Ischemia-Reperfusion Injury via the MEG3/miR-21a-5p Axis

[Biomaterials] Exosomes from the conditioned medium (CM) of gingival MSC were isolated by ultracentrifugation and were injected into the vitreous of mice. The results showed that intraocular injection of TNF-α-stimulated gingival MSC into mice with ischemia-reperfusion injury notably reduced inflammation and cell loss than that with G-exos.

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