mesenchymal stem cells

[Stem Cells International] Investigators manufactured neprilysin gene-enhanced human umbilical cord-derived MSCs and intravenously transplanted them in Aβ1-42-injected Alzheimer’s disease animal models.

[Bioengineered] Exosomes were extracted from the supernatant of the bone-marrow MSCs. The expression of the micro-RNA miR-93-3p was determined by qRT-PCR analysis.

[Biomaterials Science] Researchers reported a facile and efficient strategy for in vivo tracking the secretion of hepatocyte growth factor in MSCs during idiopathic pulmonary fibrosis therapy.

[Stem Cell Research & Therapy] A type 2 diabetes mellitus (T2DM) model was established through 28-week high-fat diet feeding resulting in T2DM-associated non-alcoholic fatty liver disease, followed by the injection of bone marrow MSCs.

[Current Stem Cell Research & Therapy] Investigators review the potential application of MSC extracellular vesicles as an emerging treatment strategy for optic neuritis by reviewing studies in multiple sclerosis and related disorders.

[Open Biology] Scientists summarize the current knowledge on fibro-adipogenic progenitors cell characteristics, heterogeneity and the cellular crosstalk during skeletal muscle homeostasis and regeneration.