mesenchymal stem cells

[Molecular Therapy-Nucleic Acids] Using unbiased transcriptome profiling of hypoxia-preconditioned MSCs and normoxic MSCs, scientists identified a lncRNA named lung cancer-associated transcript 1 (LUCAT1) under hypoxia.

[Stem Cells International] Scientists identified the preventative defensive ability and therapeutic effect of human umbilical cord mesenchymal stem cells (HUCMSCs). HUCMSCs were administered before or after bleomycin injection in different groups of C57BL/6 mice.

[Scientific Reports] Researchers compared human fibronectin adhesion assay-derived chondroprogenitors with migratory chondroprogenitors in normoxic and hypoxic culture conditions, investigating their growth characteristics, surface marker profile and trilineage potency.

[Scientific Reports] Researchers developed a protocol for processing human adipose derived MSC secretome formulation of varying concentration. Its molecular composition was evaluated, and its effectiveness in vitro using breast cancer cell lines.

[Applied Materials Today] Scientists showed that MSCs cultured in hPL displayed a reduced cell size and cell spreading, but an improved proliferation and osteogenic capability compared with cells maintained in fetal bovine serum.

[Journal of Tissue Engineering] Researchers investigated the therapeutic effects of exosomes secreted by melatonin-stimulated MSCs on the functional recovery of the kidney in a chronic kidney disease mouse model.