mesenchymal stem cells

[Stem Cell Research & Therapy] Bone-associated MSCs (BA-MSCs) were isolated from gene knockout mice, and the effect of Caspase-3/NLRP3 deficient BA-MSCs on hematopoiesis regulation was explored in vivo and ex vivo.

[Stem Cell Research & Therapy] Scientists isolated human exfoliated deciduous teeth, namely biliary atresia-SHED, using a standard colony-forming unit fibroblast method and compared characteristics as MSCs to healthy donor-derived control SHED.

[Stem Cell Research & Therapy] The authors investigated whether sevoflurane preconditioning could promote MSCs to attenuate myocardial I/R injury via transient receptor potential canonical channel 6 (TRPC6)-induced angiogenesis.

[Cancer Letters] The authors review the current knowledge regarding the involvement of exosomes secreted by MSCs in tumor progression and their potential as drug delivery systems in targeted therapy.

[Stem Cells International] Mesenchymal stem cell (MSC) transplantation therapy, which can trigger neuronal regeneration and repair, has been considered as a significant advance in treatment of ischemic stroke.

[Cell Death & Disease] The authors found that 3D human placenta-derived MSCs demonstrated a significant increase in secretion of anti-inflammatory factors and trophic factors like VEGF, PDGF, FGF via QPCR and Bio-Plex assays.