mesenchymal stem cells

[Oral Diseases] Genetic variant was identified with exome sequencing. The human dental pulp cells isolated from a patient with Cowden syndrome were investigated for their proliferation, osteogenesis, adipogenesis, and gene expression compared with controls.

[Proceedings of the National Academy of Sciences of the United States of America] Human malignant cells distributed in the bioreactor system mimicking the spatial distribution found in native bone marrow tissue, where most hematopoietic stem and progenitor cells remained linked to the niches and mature cells were released to the circulation.

[Scientific Reports] Researchers developed a robust method to generate 3D, scaffold-free, hyaline cartilage tissue constructs from human ESCs that were composed of numerous chondrocytes in lacunae, embedded in an extracellular matrix containing Type II collagen, sulphated glycosaminoglycans and Aggrecan.

[Leukemia] Scientists examined the effects of plasma from myeloma patients at diagnosis and in complete remission and from healthy donors on the osteoblastic differentiation of healthy donor-derived adipose-dervied MSCs.

[Biotechnology Journal] Murine adipose-derived MSC line m17.ASC was cultured in agarose-based microwell plates to obtain size-controlled m17.ASC spheroids of an average diameter and cell number of approximately 170 μm and 1100 cells/spheroid, respectively.

[Universityof Kansas (News-Medical.Net)] A researcher at the University of Kansas has earned a five-year, $1.25 million Maximizing Investigators' Research Award from the National Institutes of Health to study how estrogen interacts with the body at the level of the cell microenvironment.