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mesenchymal stem cells
Cell Therapy News
Effects of Single and Multiple Transplantations of Human Umbilical Cord Mesenchymal Stem Cells on the Recovery of Ovarian Function in the Treatment of Premature...
[Journal of Ovarian Research] Scientists compared the effect of single and multiple injections of human umbilical cord blood-MSCs on ovarian function repair in chemotherapy-induced premature ovarian failure.
Umbilical & Placental Cell News
Assessment of Long-Term In Vitro Multiplied Human Wharton’s Jelly-Derived Mesenchymal Stem Cells prior to Their Use in Clinical Administration
[Cells Tissues Organs] The authors analyzed cellular, molecular, and chromosomal alterations in Wharton’s jelly-derived MSCs during their in vitrosequential passages.
Umbilical & Placental Cell News
Effect of HGF-Transfected Human Umbilical Cord Mesenchymal Stem Cells on Hepatic Stellate Cells by Regulating TGF-β1/Smads Signaling Pathway
[Stem Cells and Development] Investigators explored the possible mechanism of HGF-transfected human umbilical cord MSCs in inhibiting the proliferation and activation of hepatic stellate cells-T6.
Cell Therapy News
Mesenchymal Stromal Cells as Carriers of IL-12 Reduce Primary and Metastatic Tumors of Murine Melanoma
[Scientific Reports] Scientists developed a system in which cytokine may be administered intravenously without toxic side effects. MSC were used as carriers of the IL-12.
Mesenchymal Cell News
Chromatin Remodeling Due to Degradation of Citrate Carrier Impairs Osteogenesis of Aged Mesenchymal Stem Cells
[Nature Aging] Researchers showed that aged mesenchymal stem cells exhibited reduced chromatin accessibility and lowered histone acetylation, particularly on promoters and enhancers of osteogenic genes.
Cell Therapy News
Extracellular Vesicles Derived from CD73 Modified Human Umbilical Cord Mesenchymal Stem Cells Ameliorate Inflammation after Spinal Cord Injury
[Journal of Nanobiotechnology] Effects of CD73+ human umbilical cord MSC-EVs on hydrolyzing ATP into adenosine were detected. The polarization of M2/M1 was verified by immunofluorescence.
