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mesenchymal stem cells

Analysis of the Signal Cross Talk via CCL26 in the Tumor Microenvironment in Osteosarcoma

[Scientific Reports] Investigators identified the humoral factor involved in the association between tumor cells and surrounding normal cells using a co-culture model and investigated the significance of their findings.

Mesenchymal Stem Cell Therapy for Alzheimer’s Disease

[Stem Cells International] The authors compile pertinent preclinical Alzheimer's disease research on transgenic mice as well as clinical trials on MSC-based therapy from diverse sources.

Senescent Immune Cells Release Grancalcin to Promote Skeletal Aging

[Cell Metabolism] Mechanistically, the authors found that grancalcin binds to the plexin-b2 receptor and partially inactivated its downstream signaling pathways, thus repressing osteogenesis and promoting adipogenesis of bone marrow mesenchymal stromal cells.

A Novel Study on the Immunomodulatory Effect of Umbilical Cord Derived Mesenchymal Stem Cells Pretreated with Traditional Chinese Medicine Asarinin

[International Immunopharmacology] To better understand the role of MSC in the prevention and treatment of graft-versus-host disease, umbilical cord derived MSCs were pre-treated with Chinese medicine Asarinin and IFN-γ.

The Protective Benefit of Heme Oxygenase-1 Gene Modified Human Placenta-Derived Mesenchymal Stem Cell in N-Nitro-L-Arginine Methyl Ester -Induced Preeclampsia-Like Rat Model: Possible Implications for...

[Stem Cells and Development] Investigators explored the protective benefit of heme oxygenase-1-placenta-derived MSC transplantation in a preeclampsia-like rat model.

Phenotypic, Morphological, and Metabolic Characterization of Vascular-Spheres from Human Vascular Mesenchymal Stem Cells

[Microscopy Research and Technique] Scientists tested the ability of human MSCs isolated from the vascular wall to grow as spheres, and provide a characterization of this 3D model.

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