monocytes

[PLOS Pathogens] The authors reported that CXCR3-dependent recruitment of Ly6C+ Th1 effector cells was indispensable for concomitant immunity and acute cell-phagocyte interactions were critical to prevent the establishment of a permissive pathogen niche.

[Journal of Molecular and Cellular Cardiology] Investigators performed single-cell profiling of 35,245 cells from two venous malformation samples and three cavernous venous malformation samples, with a focus on endothelial cells, smooth muscle cells and immune microenvironment.

[Cell Death Discovery] Scientists summarize the available data supporting the multiple effects of interleukin-34 in human colorectal carcinoma.

[Laboratory Investigation] Scientists investigated the roles of Lipocalin 2 (LCN2) in chronic inflammation and fibrosis, using repeated carbon tetrachloride in mineral-oil injection. Hepatic and serum LCN2 levels were remarkably higher in the mineral oil-injected wild type group compared to the CCl4.

[Cell Reports] Using DNA-label retaining, single-cell RNA sequencing, and other approaches, researchers investigated intestinal adenoma in response to chemoradiotherapy, thus identifying therapy-resistant tumor-initiating stem cells.

[Proceedings of the National Academy of Sciences of the United States of America] Investigators identified that coronavirus induced an increased Mφ-mediated inflammatory response due to a coronavirus-induced decrease in the histone methyltransferase, SETDB2.