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muscle cells
Muscle Cell News
Circular RNA hsa_circ_105039 Promotes Cardiomyocyte Differentiation by Sponging miR-17 to Regulate cyclinD2 Expression
[Molecular Medicine Reports] hsa_circ_105039 was underexpressed in the heart tissue of patients with congenital heart disease. Investigators found that hsa_circ_105039 overexpression promoted cell differentiation, viability and migration; whereas apoptosis was simultaneously repressed.
Muscle Cell News
Peroxisome Proliferator-Activated Receptor β/δ Regulates Cerebral Vasospasm after Subarachnoid Hemorrhage via Modulating Vascular Smooth Muscle Cells Phenotypic Conversion
[Molecular Medicine Reports] Subarachnoid hemorrhage grade, neurological scores, brain water content and brain swelling were measured to study the mechanisms of PPARβ/δ on vascular smooth muscle phenotypic transformation.
Muscle Cell News
Functional Effects of Cardiomyocyte Injury in COVID-19
[Journal of Virology] Scientists infected hiPSC-derived cardiomyocytes, from healthy human subjects, with SARS-CoV-2 in the absence and presence of IL-6 and IL-1β. Infection resulted in increased numbers of multinucleated cells.
Muscle Cell News
LncRNA TUG1 Aggravates Cardiomyocyte Apoptosis and Myocardial Ischemia/Reperfusion Injury
[Histology and Histopathology] Researchers reported that TUG1 expression was induced in mouse heart following myocardial ischemia/reperfusion injury as well as in cardiomyocytes subjected to simulated ischemia/reperfusion in vitro.
Muscle Cell News
Smooth Muscle 22 Alpha Protein Inhibits VSMC Foam Cell Formation by Supporting Normal LXRα Signaling, Ameliorating Atherosclerosis
[Cell Death & Disease] Researchers found a potential association between deletion of smooth muscle 22α and deregulated nuclear receptors liver X receptors /retinoid X receptor signaling in mice.
Immune Regulation News
PD-L1 (Programmed Death Ligand 1) Regulates T Cell Differentiation to Control Adaptive Venous Remodeling
[Arteriosclerosis Thrombosis and Vascular Biology] In the mouse aortocaval fistula model, anti-PD-L1 antibody was given to inhibit PD-L1 activity during arteriovenous fistulae maturation.