muscle cells

[NPJ Regenerative Medicine] To examine the effects of chronic 4-hydroxytamoxifen treatment, researchers used state-of-the-art human-induced pluripotent stem cell-derived cardiomyocytes and a bioengineered platform to model duchenne muscular dystrophy.

[NPJ Genomic Medicine] Scientists analyzed whole-genome sequencing data in a discovery cohort of 209 pediatric cardiomyopathy patients and 1953 independent replication genomes and exomes and searched for protein-coding variants and non-coding variants predicted to affect the function or expression of genes.

[Acta Pharmacologica Sinica] Researchers investigated whether sotagliflozin, an anti-hyperglycemia SGLT2 inhibitor, exerted therapeutic angiogenesis effects in diabetic HLI in vitro and in vivo.

[Science Advances] The authors analyzed the role of galectin-1, a β-galactoside–binding protein, as a therapeutic target for atherosclerosis and abdominal aortic aneurysm.

[Inflammation] Investigators focused on how miR-98-5p functioned in the proliferation and migration of human airway smooth muscle cells treated with interleukin-13 (IL-13).

[Journal of Biochemical and Molecular Toxicology] Catalpol promoted the viability and reduced cell apoptosis of human cardiomyocyte AC16 cells and repressed the release of inflammatory cytokines TNF-α, IL-6, and IL-1β, while inhibiting the leakage of myocardial injury markers lactate dehydrogenase and creatine kinase.