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muscle cells

Injectable Laminin-Biofunctionalized Gellan Gum Hydrogels Loaded with Myoblasts for Skeletal Muscle Regeneration

[Acta Biomaterialia] Researchers proposed an in situ-crosslinking gellan gum-based hydrogel tethered with a skeletal muscle-inspired laminin-derived peptide RKRLQVQLSIRTC(Q) and encapsulated with skeletal muscle cells.

Glucocorticoids Rapidly Promote YAP Phosphorylation via the cAMP-PKA Pathway to Repress Mouse Cardiomyocyte Proliferative Potential

[Molecular and Cellular Endocrinology] Researchers showed that glucocorticoids suppressed cardiomyocyte (CM) proliferation in vitro and in vivo, decreased the total number of CMs, and increased the cross-sectional area of CMs.

LncRNA Rian Reduces Cardiomyocyte Pyroptosis and Alleviates Myocardial Ischemia–Reperfusion Injury by Regulating by the miR-17-5p/CCND1 Axis

[Hypertension Research] The authors investigated the mechanism of long noncoding RNAs Rian in myocardial ischemia–reperfusion injury-induced cardiomyocyte pyroptosis.

Metabolic Determinants of Cardiomyocyte Proliferation

[Stem Cells] Scientists provide knowledge of the regulatory mechanisms that control substrate partitioning to coordinate biosynthesis with energy provision could be leveraged to prompt or augment cardiomyocyte division and to promote cardiac repair.

SIRT1 Regulates Cardiomyocyte Alignment during Maturation

[Journal of Cell Science] Researchers reported that SIRT1, the most conserved NAD+-dependent protein deacetylase highly expressed in perinatal heart, played an important role in regulating cardiomyocyte remodeling during development.

Vascular Hyperacetylation Is Associated with Vascular Smooth Muscle Dysfunction in a Rat Model of Non-Obese Type 2 Diabetes

[Molecular Medicine] THe authors hypothesized that vascular smooth muscle cell undergoes dysregulation in advanced type 2 diabetes mellitus which was associated with vascular hyperacetylation.

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