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myeloid cells

Hofbauer Cells and Coronavirus Disease 2019 (COVID-19) in Pregnancy: Molecular Pathology Analysis of Villous Macrophages, Endothelial Cells, and Placental Findings from 22 Placentas Infected...

[Archives of Pathology & Laboratory Medicine] SARS-CoV-2 could extend beyond the trophoblast into the villous stroma, involving Hofbauer cells and capillary endothelial cells, in a small number of infected placentas.

hucMSC-Derived Exosomes Attenuate Colitis by Regulating Macrophage Pyroptosis via the miR-378a-5p/NLRP3 Axis

[Stem Cell Research & Therapy] Human umbilical cord MSC-derived exosomes carrying miR-378a-5p inhibited NLRP3 inflammasomes and abrogated cell pyroptosis to protect against DSS-induced colitis.

Super Enhancer Regulation of Cytokine-Induced Chemokine Production in Alcoholic Hepatitis

[Nature Communications] Researchers explored the mechanistic role of super-enhancers linking cytokine TNFα with chemokine amplification in alcoholic hepatitis.

Ly6G Deficiency Alters the Dynamics of Neutrophil Recruitment and Pathogen Capture during Leishmania major Skin Infection

[Scientific Reports] Researchers showed that Ly6G deficiency decreased the initial infection rate of neutrophils recruited to the site of skin infection.

Lymphoid and Myeloid Immune Cell Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation

[Bone Marrow Transplantation] Investigators evaluated the immune reconstitution of patients receiving omidubicel grafts during the first six months post-transplant, as IR is critical for favorable outcomes of the procedure.

Neuroblastoma Formation Requires Unconventional CD4 T Cells and Arginase-1-Dependent Myeloid Cells

[Cancer Research] To understand the different facets of immune-tumor collaboration through genetics, spatial transcriptomics, and immunological manipulation with non-invasive, longitudinal imaging, the authors generated a penetrant double oncogene-driven autochthonous model of neuroblastoma.

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