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myeloid cells

Functional Characterization of the Biogenic Amine Transporters on Human Macrophages

[JCI Insight] The authors investigated the function of norepinephrine and dopamine transporters on human monocyte-derived macrophages.

Neutrophils as Potential Therapeutic Targets in Hepatocellular Carcinoma

[Nature Reviews Gastroenterology & Hepatology] The authors outline the evidence in support of neutrophils as drivers of hepatocellular carcinoma and detail their mechanistic roles in development, progression and metastasis, highlighting the reasons that neutrophils are well worth investigating despite the challenges associated with studying them.

Engineering Immunomodulatory and Osteoinductive Implant Surfaces via Mussel Adhesion-Mediated Ion Coordination and Molecular Clicking

[Nature Communications] A dual-effect coating with immobilized immunomodulatory metal ions and osteoinductive growth factors was designed via mussel adhesion-mediated ion coordination and molecular clicking strategy.

Exosomes from Adipose-Derived Mesenchymal Stem Cells Alleviate Sepsis-Induced Lung Injury in Mice by Inhibiting the Secretion of IL-27 in Macrophages

[Cell Death Discovery] The authors investigated the mechanism of exosomes from adipose-derived MSCs in sepsis-induced acute lung injury.

Blockade of Beta-Adrenergic Receptors Reduces Cancer Growth and Enhances the Response to Anti-CTLA4 Therapy by Modulating the Tumor Microenvironment

[Oncogene] Investigators showed that oral administration of propranolol delayed tumor progression of MCA205 fibrosarcoma model and MC38 colon cancer model and increased the survival rate of tumor bearing mice.

Exosomal hsa_circ_0004658 Derived from RBPJ Overexpressed-Macrophages Inhibits Hepatocellular Carcinoma Progression via miR-499b-5p/JAM3

[Cell Death & Disease] Scientists assessed the role of exosomes derived from recombination signal binding protein-Jκ (RBPJ)-overexpressed macrophages in hepatocellular carcinoma.

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