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myocardial infarction

Vascular Endothelial Growth Factor Ameliorated Palmitate-Induced Cardiomyocyte Injury via JNK Pathway

[Animal] To investigate the preservative effects of vascular endothelial growth factor sensitization on ceramide-mediated programmed cell death of cardiomyocytes, palmitate-induced injury in H9c2 cells was established as an in vitro model.

VE-Cadherin Is Required for Cardiac Lymphatic Maintenance and Signaling

[Circulation Research] VE-cadherin was an essential scaffolding protein to maintain pro-lymphangiogenic signaling nodes at the plasma membrane, which was required for the development and adult maintenance of cardiac lymphatics, but not for cardiac function basally or after injury.

A Fresh Look at Coronary Microembolization

[Nature Reviews Cardiology] The authors characterize the features and mechanisms of coronary microembolization and discuss the clinical trials of drugs and devices for prevention and treatment.

Hif-1a Suppresses ROS-Induced Proliferation of Cardiac Fibroblasts Following Myocardial Infarction

[Cell Stem Cell] Investigators reported that cardiac fibroblasts and mesenchymal progenitors are more hypoxic than other cardiac interstitial populations, express more hypoxia-inducible factor 1α (HIF-1α), and exhibited increased glycolytic metabolism.

A Fluid-Powered Refillable Origami Heart Pouch for Minimally Invasive Delivery of Cell Therapies in Rats and Pigs

[Med] Scientists developed a fluid-driven heart pouch with a memory-shaped microfabricated lattice structure inspired by origami. The pore size of the membrane was around 0.4 μm, which allowed for the penetration of growth factors and exosomes.

Forensic Significance of Intracardiac Heme Oxygenase-1 Expression in Acute Myocardial Ischemia

[Scientific Reports] The authors examined the immunohistochemical expression of heme oxygenase-1 in the heart samples to discuss their forensic significance to determine acute cardiac ischemia.

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