neural cells

[Scientific Reports] Scientists used a well-established rat model to expose mother dams to alcohol, nicotine-alcohol, and saline perinatally. Dopamine (DA) and non-DA neurons collected from the ventral tegmental area (VTA) of the rat pups were used to study expression profiles of miRNAs and mRNAs.

[Science] The authors reasoned that the expansion of new neuronal types occurred in a stepwise manner analogous to animal speciation, and they explored this by defining transcriptomic relationships using a top-down approach.

[Proceedings of the National Academy of Sciences of the United States of America] Investigators demonstrated that mouse microglia exhibited temperature-dependent movement in vitro and in vivo that was mediated by TRPV4 channels within the physiological range of body temperature.

[Cell] Scientists investigate the role of chaperone-mediated autophagy, a selective autophagy shown to degrade neurodegeneration-related proteins, in neuronal proteostasis.

[Stem Cell Reports] The authors assessed the importance of sequestosome-1 (SQSTM1/p62) in human induced pluripotent stem cell-derived cortical neurons through the knockout of SQSTM1.

[Scientific Reports] Researchers investigated the acute effects of the opioid analgesic buprenorphine on diffuse neuronal/glial pathology, neuroinflammation, cell damage, and systemic physiology.