neural cells

[Nature] Scientists used organoid models of the human cerebral cortex to identify cell-type-specific developmental abnormalities that result from haploinsufficiency in three autism spectrum disorder risk genes—SUV420H1, ARID1B and CHD8—in multiple cell lines from different donors.

[Scientific Reports] The authors suggested that transcriptomic profiling could provide novel information source for studying the neuropathogenesis of enterovirus-A71 infection leading to development of an effective therapeutic measure for central nervous system complications.

[Cell Death & Disease] To investigate the role of myeloid cell MANF in the pathogenesis of AILI, researchers assayed serum and liver samples from acetaminophen-induced liver injury model mice and patients with drug-induced liver injury.

[Frontiers in Bioscience-Landmark] Researchers determined live cell metabolism and bioenergetics in pathophysiological relevant, WNT-dependent glioblastoma stem cell models.

[Nature Communications] Scientists found that depletion of Fbl, an rRNA methyltransferase, reduced translation of both Ezh2 methyltransferase and Kdm6b demethylase of H3 trimethylation in Lys27 and delayed the progression of the neural stem cell state.

[Current Stem Cell Research & Therapy] The authors explored the contribution of miRNAs in adipose-derived stem cell-extracellular vesicles to the treatment of cerebral ischemia.