neural cells

[Chemosphere] The authors summarize the effects of nanomaterials on the proliferation and differentiation of ESCs, mesenchymal stem cells and neural stem cells.

[Scientific Reports] Scientists analyzed the physiological role of Wdr45 and pathophysiological significance of the gene abnormality during mouse brain development. Morphological and biochemical analyses revealed that Wdr45 was expressed in a developmental stage-dependent manner in mouse brain.

[Nature Communications] Investigators reported the development of a complete labeling and imaging pipeline using genetic code expansion and non-canonical amino acids in neurons that allows to fluorescently label masked epitopes in target transmembrane proteins in live neurons, both in dissociated culture and organotypic brain slices.

[Nature Neuroscience] Using transplantation of wild-type (WT) neurons, the authors showed that amyloid beta (Aβ) entered WT grafts, and that this was accompanied by microglia infiltration.

[Cell Reports] In cell transplantation therapy for spinal cord injury, grafted human induced pluripotent stem cell-derived neural stem/progenitor cells (hiPSC-NS/PCs) differentiate into neurons. Scientists found that chemogenetic stimulation of hiPSC-derived neural cells enhancesd cell activity and neuron-to-neuron interactions in vitro.

[iScience] Investigators reported that irradiation with a single-frequency Terahertz laser on mice cortical neuron cultures increased excitatory synaptic transmission and neuronal firing activities.