neurons

[Biophysical Journal] Transient receptor potential vanilloid 4 (TRPV4) enabled endothelial cells, smooth muscle cells, and perivascular neurons, to integrate hemodynamic forces to regulate systemic blood pressure.

[Journal of Cell Biology] Scientists devised a straightforward bioengineered neural organoid culture approach entailing transcription factor–driven direct differentiation of neurons and astrocytes from human PSC combined with genetically encoded tools for dual cell-selective activation.

[Neuron] Investigators demonstrated that neuronal NPF in Drosophila exerted a conservative immunomodulatory effect.

[Brain] To model human malformations of cortical development associated with nitrogen permease regulator-like 3 (NPRL3) variants, researchers created a focal Nprl3 KO in fetal mouse cortex by in utero electroporation and found altered cortical lamination and white matter heterotopic neurons

[Brain] Scientists revealed a previously undefined cell type-specific role of 2-arachidonoylglycerol metabolism and signaling pathways in traumatic brain injury-induced neuropathology.

[Neuron] The authors review how the different autophagic pathways may protect against neurodegeneration, giving examples of both polygenic and monogenic diseases.